Clinical History

This unique, biocompatible End-Point™ Bonded Heparin Coating and bonding process has been used successfully in a wide range of medical devices, including vascular grafts (1,2,3), coronary stents(4), ventricular assist devices(5) and blood oxygenators(6,7).

1. W. L. Gore GORE-TEX® PROPATEN vascular graft. Walluscheck, K. P., Bierkandt, S., Brandt, M., Cremer, J., Infrainguinal ePTFE Vascular Graft with Bioactive Surface Heparin Bonding: first clinical results, J Cardiovasc Surg (Torino), 2005, 46: 425-430
2. W. L. Gore GORE-TEX® PROPATEN vascular graft. Bosiers, M., MD, Deloose, K., MD, Verbst, J., MD, Schroe, H., MD, Lauwers, G., MD, Lansink, W., MD, Peeters, P., MD, Heparin-Bonded Expanded Polytetrafluoroethylene Vascular Graft for Femoropopliteal and Femorocrural Bypass Grafting: 1-Year Results. J Vasc Surg, Feb. 2006, 43: 313-318
3. W. L. Gore GORE-TEX® PROPATEN vascular graft. Patency of Below-Knee Bypasses with the GORETEX ® PROPATEN Vascular Graft: Literature Summary, May 2006, W. L. Gore & Associates, Inc.
4. Cordis Bx VELOCITY™ coronary stent with HEPACOAT™ Carmeda® coating. Kocsis, J., Llanos, G., Holmer, E., Heparin-Coated Stents, Journal of Long-Term Effects of Medical Implants, 2000, 10: 19-45
5. Berlin Heart EXCOR® VAD system. Kaufman, F., Hennig, E., Leobe, M., Hetzer,R., Improving the Antithrombogenity of Artificial Surfaces Through Heparin Coating - Clinical Experience with the Pneumatic Extracorporeal Berlin Heart Assist Device, Cardiovascular Engineering, Dec. 1996, 1: 40-44
6. Medtronic Carmeda® Affinity® NT Oxygenator. Saenz, A., Larranaga, G., Alvarez, L., Greco, E., Marrero, A., Lunar, M., Elosegui, C., Ubago, J. L., Gallo, I., Heparin-Coated Circuit in Coronary Surgery. A clinical study. Eur J Cardiothorac Surg, 1996, 10: 48-53
7. Heparin-coated cardiopulmonary bypass. Miyaji, K., MD, Hannan, R. L., MD, Ojito, J., BSCCP, Jacobs, J. P., MD, White, J. A., MS, Burke, R. P., MD, Heparin-Coated Cardiopulmonary Bypass Circuit: Clinical Effects in Pediatric Cardiac Surgery, J Card Surg, 2000, 15: 194-198